The game natively supports 4:3 resolutions. To play in 1080p, 1440p, or 4K, use the Path of Neo Widescreen Fix by ThirteenAG from the ThirteenAG repository. This script injects custom resolutions and fixes the Aspect Ratio.
As of 2025, the modding scene remains niche but active. A project called "Neo Re-Entered" is currently attempting to reverse-engineer the game’s executable to allow for total conversion mods—similar to how Half-Life mods became standalone games.