Overprotective security software (like Avast or Malwarebytes) may flag the .exe as a threat and block its execution.
If none of the above work, dig deeper:
Before proceeding, it is important to address security concerns. The legitimate s1-sp64-ship.exe is not a virus; it is a core component of the game you are trying to play. However, malware can disguise itself with similar names. s1-sp64-ship.exe error