Do not run the installer straight from a CD or an ISO mount. Copy the full contents of the STEP 7 V5.5 installation media directly into a local storage folder on your primary drive ( C:\Step7Installation\ ). Step7 V5.5 SP4 on Windows 10 - SiePortal
Run a guest OS (Windows 7 or XP) within the VM and install STEP 7 V5.5 there to ensure stable driver performance and project integrity. : step 7 v 5.5 windows 10