Led by Megatron, featuring high-ranking officers like Starscream, Soundwave, and Shockwave.

Critical devices needed to activate the Omega Lock and restore life to Cybertron.

Developed by and Alex Kurtzman , the show centers on "Team Prime," a small band of Autobots hiding on Earth who protect the planet from a resurgent Decepticon threat while mentoring three human teenagers: Jack, Miko, and Raf. Comprehensive Episode Index

| Name | Voice Actor | Role | Status (End of Series) | | :--- | :--- | :--- | :--- | | Optimus Prime | Peter Cullen | Leader | Ascended (Joined Allspark) | | Arcee | Sumalee Montano | Two-Wheeler | Alive | | Bulkhead | Kevin Michael Richardson | Heavy Muscle | Alive | | Bumblebee | Will Friedle | Scout | Alive | | Ratchet | Jeffrey Combs | Medical Officer | Alive | | Wheeljack | James Horan | Wrecker | Alive | | Ultra Magnus | Michael Ironside | Commander | Alive | | Smokescreen | Nolan North | Young Soldier | Alive |